9 month infant admitted for skin abscess. What is the hematologic diagnosis? Name the hematologic index that would help further test for this diagnosis.
Hint:
The six discrimination indices are:
WBC (K/CMM)
|
7.8
|
RBC (M/CMM)
|
4.66
|
Hb (g/dL)
|
9.7
|
HcT (%)
|
29.6
|
MCV (fL)
|
63.5
|
MCH (pg)
|
20.8
|
MCHC (g/dL)
|
32.7
|
RDW (%)
|
17.0
|
PLT (K/CMM)
|
211
|
MPV (fL)
|
8.3
|
Hint:
The six discrimination indices are:
- Mentzer Index (MI): MCV / RBC
- Green & King Index (G&K): MCV × RDW / (Hb × 100)
- RDW Index (RDWI): MCV × RDW / RBC
- England & Fraser Index (E&F): MCV − RBC-(5 × Hb) − k [k = 6.4]
- RDW
- RBC count
Based on one of the above index what is next test to order?
1. Hb A2 (Hemoglobin electrophoresis)
2. serum ferritin
3. vitamin B12
4. bone marrow aspiration
5. serum lead