Tuesday, January 28, 2014

"Rash"ionale - 2

How do you differentiate urticarial rash from Erythema multiforme?






What is the role of corticosteroid treatment?





Name a bacterial cause.



Arch Dis Child 96:i34-i37 doi:10.1136/adc.2011.214734

Monday, July 15, 2013

Lessons from the cat

4year child with Tracheotomy on home ventilator. His parent had difficulty in putting back the dislodged tracheotomy tube.




Describe "Macklin effect".


Hint: Drawn by the author in his original paper


credit:
Can Med Assoc J. 1937 April; 36(4): 414–420.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1562024/

Wednesday, April 24, 2013

Asthma comorbidity

7yr girl with asthma but has inspiratory dyspnea as well


This is a spirometry  (illustration is not related to this patient)







Hint:

What phase of breathing does stridor usually manifest?

Resource:

Wheezing and vocal cord dysfunction mimicking asthma
PMID: 11140406 [PubMed - indexed for MEDLINE]

Friday, January 4, 2013

"Rash"ionale 1

This is an infant on a parent lap. (The following questions are not linked to each other and describes seperate entity)









1.What is the most life saving management if the child is "ill appearing" with high fever?



2.What is the role of steroids if your diagnosis is a "vasculitis disorder" in a well appearing child?

http://www.ncbi.nlm.nih.gov/pubmed/22311342


3. Name the childhood vaccine associated with "autoimmune" disease presenting like this.


4. What is the indication for bone marrow aspiration in this child?
1998 Apr;152(4):345-7.









Saturday, December 15, 2012

Blood teaser

9 month infant admitted for skin abscess. What is the hematologic diagnosis?  Name the hematologic index that would help further test for this diagnosis.




WBC  (K/CMM)
7.8
RBC  (M/CMM)
4.66
Hb  (g/dL)
9.7
HcT (%)
29.6
MCV (fL)
63.5
MCH (pg)
20.8
MCHC (g/dL)
32.7
RDW (%)
17.0
PLT (K/CMM)
211
MPV (fL)
8.3



Hint:

The six discrimination indices are:
  • Mentzer Index  (MI): MCV / RBC
  • Green & King Index (G&K): MCV  × RDW / (Hb × 100)
  • RDW Index (RDWI): MCV × RDW / RBC
  • England & Fraser Index  (E&F): MCV − RBC-(5 × Hb) − k [k = 6.4]
  • RDW
  • RBC count
 
 
Based on one of the above index what is next test to order?
 
1. Hb A2 (Hemoglobin electrophoresis)
2. serum ferritin
3. vitamin B12
4. bone marrow aspiration
5. serum lead

Monday, December 3, 2012

Nagging neck pain



10 yr old boy  with neck pain and high fever. He had two weeks of upper respiratory tract infection.







What is the diagnosis? And identify the markers.

Wednesday, November 14, 2012

What is the diagnosis?

5 year old with massive hepatomegaly






CT Abdomen shows increased vascularity and calcification in the liver.