Tuesday, September 30, 2014

"Add it up"

17 year old with sickle cell anemia, ADHD and Asthma admitted to intensive care for acute chest syndrome and asthma exacerbation. His social history is concerning for compliance and also not having a stable family.

Medication at home:
Impiramine
Albuterol prn

 

CBC:

Detail

Value w/Units

Normal Range

WBC
24.6 K/CMM
4.5-13.5
RBC
2.53 M/CMM
4.20-5.40
Hgb
7.6 g/dL
11.5-15.5
Hct
20.4 %
34.5-46.5
MCV
80.7 fL
75.0-95.0
MCH
30.1 pg
27.0-31.0
MCHC
37.2 g/dL
32.0-36.0
RDW
23.9 %
11.5-14.5
Platelet
353 K/CMM
133-450
MPV
9.0 fL
7.4-10.4

 

Hemoglobin electrophoresis:

Detail

Value w/Units

Normal Range

Hgb S %
84.8 %
0.0-0.0
Hgb A %
4.5 %
95.8-97.8
Hgb A2 %
3.2 %
2.2-3.2
Hgb F %
7.5 %
0.0-1.0
Hgb C %
0.0 %
0.0-0.0

 

 

 

What is the appropriate intervention?

A. Start antibiotics for high WBC
B. Add penicillin prophylaxis
C. Obtain Bone Marrow biopsy
D. Start hydroxyurea
E. None of the above
 

Reference:

http://pediatrics.aappublications.org/content/122/6/1332.short

 

 

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